Restylane Refyne and Restylane Defyne

Restylane Refyne and Restylane Defyne are next generation FDA-approved dermal fillers designed to treat moderate to severe facial wrinkles and folds. Both fillers use XpresHAn Technology. This technology customizes the degree of HA (Hyaluronic acid) cross-linking in each product, resulting in gels with a range of flexibility and support characteristics for different patient needs.

While Resylane Refyne is formulated to treat less severe shallower lines and wrinkles, using a more flexible gel, Restylane Defyne is formulated for patients with deeper more severe lines and wrinkles using a less flexible gel that provides additional support.

Both fillers result in a more youthful natural looking appearance.

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Affiliated with the University of Miami Frost Department of Dermatology